Vitex

Common Names: Chasteberry, Chaste tree, Vitex, Monk's Pepper, VAC

Latin Name: Vitex agnus-castus

Description

Vitex, also known as Chaste Tree, Chasteberry, or Vitex agnus-castus, is a plant traditionally used for various health purposes, particularly in women's health. Most plants in the genus Vitex are shrubs or arbors. Vitex is often promoted as a dietary supplement for symptoms of premenstrual syndrome, breast pain associated with the menstrual cycle, infertility, and other conditions.

Health Benefits

Bioactive compounds present in Vitex plant matrix, such as iridoids, diterpenoids, ecdysteroids, and flavonoids, are reported to possess antibacterial, anti-inflammatory, antifungal, antioxidant, and anticancer properties. One of the most common uses of Vitex is to support hormonal balance, especially in women. It is believed to influence the pituitary gland, which regulates the body's balance of estrogen and progesterone. This can be particularly helpful for women experiencing hormonal imbalances. Some women with Polycystic Ovary Syndrome (PCOS), a common endocrine disorder, may use Vitex to manage symptoms related to irregular periods and hormonal imbalances. Preliminary studies suggest that it might be helpful for symptoms of premenstrual syndrome and breast pain related to the menstrual cycle, but the evidence is not conclusive. (NCCIH) 

Vitex is often used to help regulate irregular menstrual cycles. Some studies suggest that Vitex may alleviate symptoms of PMS, such as mood swings, irritability, breast tenderness, and bloating. It is thought to work by modulating hormonal fluctuations during the menstrual cycle. Vitex may have a positive impact on mood and stress levels, possibly by influencing neurotransmitters in the brain. 

It's important to note that while many people find Vitex beneficial, individual responses can vary. It’s advised to consult with a healthcare professional before incorporating Vitex into your routine. It may not be safe for women with hormone-sensitive conditions, such as breast, uterine, or ovarian cancer. 

The most well-recognized and researched species of Vitex 

  • Vitex negundo L

  • Vitex agnus-castus L

  • Vitex trifolia L

  • Vitex rotundifolia

  • Vitex cymosa Bertero ex Spreng

  • Vitex peduncularis Wall. Ex Schauer

Side effects

The most frequent adverse events are nausea, headache, gastrointestinal disturbances, menstrual disorders, acne, pruritus, and erythematous rash. No drug interactions were reported. Use of Vitex agnus castus L should be avoided during pregnancy or lactation. (Daniele) Scientific evidence for its effectiveness is still evolving, but studies continue to investigate the efficacy of Vitex.

Sources

Daniele C, Thompson Coon J, Pittler MH, Ernst E. Vitex agnus castus: a systematic review of adverse events. Drug Saf. 2005;28(4):319-32. doi: 10.2165/00002018-200528040-00004. PMID: 15783241.

Kamal N, Mio Asni NS, Rozlan INA, Mohd Azmi MAH, Mazlan NW, Mediani A, Baharum SN, Latip J, Assaw S, Edrada-Ebel RA. Traditional Medicinal Uses, Phytochemistry, Biological Properties, and Health Applications of Vitex sp. Plants (Basel). 2022 Jul 26;11(15):1944. doi: 10.3390/plants11151944. PMID: 35893648; PMCID: PMC9370779. 

NCCIH, “Chasteberry.” NCCIH, www.nccih.nih.gov/health/chasteberry.